Ubro Red®

The mastitis environment is challenging

Gram-positive Strep. uberis and gram-negative E. coli together are responsible for more cases of clinical and sub-clinical mastitis than any other pathogen.¹

The link between dry cow infections and milking cow mastitis³

Adapted from Bradley & Green 20104

Herds with a low BMSCC may have a reduced immune response, increasing their risk of environmental mastitis, leading to:⁵

• Greater risk of E. coli mastitis²
• Increased risk of toxic mastitis⁵
• Mastitis may be clinically more severe²

Ubro RED combines three antibiotics, providing effective treatment of, and protection from, both gram-negative and gram-positive pathogens

• Only Ubro RED provides antibiotic protection against E.coli for up to 14 weeks6
• The framycetin in Ubro RED persists above the E.coli MIC* for up to 14 weeks after application in the majority of udders

• Ubro RED significantly reduces the incidence of gram-negative E. coli in the first 100 days of the next lactation7
• Cows dried off with Ubro RED are half as likely to develop Coliform mastitis compared to cows dried off with 600mg of cloxacillin7,f
• Ubro RED was equally as effective against gram-positive pathogens compared to 600mg of cloxacillin7,f

*MIC = minimum inhibitory concentration

Ubro RED helps stop you slipping into the red

• The cost of treating a case of mastitis averages £250-£3008
• A cost saving of £1,460 (€1,606c)d per 100 cows per year can be achieved by using Ubro RED, compared to 600mg of cloxacillin, for Coliform mastitis alonee,7,8

Ubro RED a powerful combination of three antibiotics that:

• Provides proven protection against environmental mastitis7
• Breaks the link between dry cow infection and milking cow mastitis7
• Significantly reduces the incidence of E. coli in the first 100 days of lactation7
• Also controls gram-positive pathogens with equal efficacy to 600mg cloxacillinf,7
• Helps stop your clients slipping into the redd,7,8

Faced with the challenge of E. coli and Strep. uberis make Ubro RED your choice of dry cow therapy.

References

1. In the case of E.coli mastitis infections
2. Intramammary infection
3. Correct at June 2010 (£1 = €1.10)
4. Cost reduction was calculated as the reduction in mastitis cases achieved using Ubro RED when compared to cloxacillin 600mg (Pfizer Ltd) multiplied by the cost of a mastitis case
5. Clinical Coliform mastitis was reduced by approx 50%7
6. Cloxacillin 600mg (Pfizer Ltd)

1. Vale Veterinary Laboratory Data 2009/2010.
2. Barkema HW et al. J Dairy Sci 1998;81:411-419.
3. Bradley AJ & Green MJ. J Dairy Sci 2000;83:1957-1965.
4. Bradley AJ & Green MJ Irish Veterinary Journal (2010) vol 63 Number 6.
5. Tadich NA et al. Veterinary record 1998;143:362-365.
6. Bradley AJ & Green MJ. In Practice 2003. p12-17.
7. Bradley AJ & Green MJ. J Dairy Sci;84:1632-1639.
8. htttp://www.dairyco.org.uk/farming-info-centre/health-welfare/mastitis.aspx. Accessed June 2010.

^§ In vitro

Advice on the use of Ubro RED or other therapies should be sought from your veterinary surgeon. Ubro RED contains framycetin sulphate, penethamate hydriodide and procaine penicillin. Prescription only medicine. Further information is available from Boehringer Ingelheim Vetmedica, Bracknell, Berks, RG12 8YS. Email: vetmedica.uk@boehringer-ingelheim.com. Date of preparation: Apr 2011
Use Medicines Responsibly (www.noah.co.uk/responsible)